Top 10 Funding Rounds: Therapeutics & AI Lead Amid Slowdown

Crunchbase

The venture capital landscape saw a notable shift this past week, as the flurry of “mega-rounds” that have recently dominated headlines took a discernible pause. While whispers of colossal financings for prominent AI unicorns continue to circulate, none formally closed between August 9th and 15th. Nevertheless, the period was far from quiet, with substantial deals announced across a diverse array of sectors, most notably therapeutics, enterprise software, rare earth magnets, and, of course, artificial intelligence.

Healthcare and biotech ventures demonstrated particular strength, attracting significant capital infusions. Valencia, California-based SetPoint Medical, a developer of innovative therapies for rheumatoid arthritis and other autoimmune conditions, led the pack, securing a formidable $140 million. This sum comprised a $115 million Series D round, spearheaded by Elevage Medical Technologies and Ally Bridge Group, complemented by a $25 million second tranche of its Series C. In a related medical device development, Milford, Massachusetts’ Reprieve Cardiovascular, focused on treating acute decompensated heart failure, raised $61 million in Series B funding led by Deerfield Management, earmarked to advance its crucial clinical trials. Women’s health also saw a boost with Gameto, an Austin, Texas-based startup exploring stem cell-derived therapies for reproductive health and menopause-related symptoms, closing a $44 million Series C round led by Overwater Ventures. Further demonstrating the sector’s breadth, Jocasta Neuroscience, working on a proprietary longevity protein to address cognitive impairment in neurodegenerative diseases, secured $35 million in Series A funding, with True Ventures at the helm.

The enterprise software and AI sectors continued to draw substantial investment, reflecting the ongoing digital transformation across industries. Titan, a New York-based startup specializing in AI-enabled tools for IT services, garnered $74 million from General Catalyst, a deal that notably coincided with its acquisition of RFA, a provider of IT and cybersecurity services for the financial sector. In the realm of digital identity, Iselin, New Jersey’s 1Kosmos, a pioneer in passwordless authentication solutions, raised $57 million in Series B funding, including a $10 million line of credit. The equity investment was led by Forgepoint Capital and Oquirrh Ventures, while Bridge Bank provided the debt financing. FieldPulse, a Dallas-based provider of mobile-optimized software for managing field services teams, saw its business double year-over-year, culminating in a $50 million Series C round led by Fulcrum Equity Partners. Two San Francisco-based AI startups also made significant strides: XOps, emerging from stealth with $40 million in funding co-led by Activant Capital and FPV Ventures, aims to automate IT operations, while Squint, which develops software to automate tasks in manufacturing, closed a $40 million Series B with co-leads The Westly Group and TCV.

Beyond these dominant sectors, more specialized technologies also secured substantial backing. Durham, North Carolina’s Vulcan Elements, a manufacturer of rare earth magnets, picked up $65 million in Series A funding at a $250 million valuation. Altimeter led the financing for the company, which already holds contracts to supply its magnets to the military, highlighting the strategic importance of its technology. In a particularly forward-looking investment, New York-based Profound raised $35 million in a Series B round led by Sequoia Capital for its platform designed to market to AI “superintelligence” rather than human consumers, signaling a nascent but intriguing area of future commercialization.

This week’s funding activities underscore the continued, robust flow of venture capital into innovative companies across the U.S., even as the market takes a breather from the headline-grabbing mega-deals. The focus remains firmly on advancements in health, enterprise efficiency, and the ever-expanding applications of artificial intelligence, illustrating a healthy, if less flamboyant, investment landscape.